Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 222-573-8 | CAS number: 3536-49-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
Not toxic for reproduction.
Additional information
As reported in EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) no adverse effect were observed in 65 male and female mice oral treated by 150, 500 and 1500 mg/kg bw/day of the test item for 9 weeks. Based on this study, the NOAEL of reproductive toxicity is 1500 mg/kg bw/day.
Effects on developmental toxicity
Description of key information
Not toxic for development.
Additional information
A developmental toxicity study is reported in the document EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS): the NOAEL of developmental toxicity of the test item is 500 mg/kg bw/day.
Justification for classification or non-classification
Not classified for reproductive and developmental toxicity according to the CLP Regulation (EC.1272/2008). For justification see additional information.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
