Registration Dossier
Registration Dossier
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EC number: 222-573-8 | CAS number: 3536-49-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Results of available in vitro studies:
- Ames test for the strain TA 98 in the presence of metabolic activation S9 at 5000 µg/plate: positive.
- Mammalian cell gene mutation test: negative.
- Ames test for the strain TA 98 in presence and absence of metabolic activation S9 at 5000 µg/plate: negative.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Description of key information
Results of available in vitro study:
Single cell gel/Comet assay in rats: negative.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
Justification for classification or non-classification
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. No hazard for genotoxicity was identified. As a result, according to the CLP Regulation (EC 1272/2008), the substance is not considered to be classified for genetic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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