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Physical & Chemical properties

Dissociation constant

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Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
no data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Principles of method if other than guideline:
Method: other: Potentiometric determination of the ionization constant
GLP compliance:
no
Dissociating properties:
yes
Remarks on result:
other: Acid-base constant: Ka= 2.5 ± 0.3 x 10-5 at 25 ± 0.2 °C and zero ionic strength
Conclusions:
Acid-base constant: Ka= 2.5 ± 0.3 x 10-5 at 25 ± 0.2 °C and zero ionic strength

Description of key information

Halamid (N-chloro-4-methylbenzenesulfonamide sodium)'s Acid-base constant: Ka= 2.5 ± 0.3 x 10-5 at  25 ± 0.2 °C and zero ionic strength

Key value for chemical safety assessment

pKa at 20°C:
0.39

Additional information