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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 202-809-6 | CAS number: 100-00-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Unsuitable test system (more than one substance tested in the same vessel). BCF for p-chloronitrobenzene cannot be derived with this test design; adopted according to OECD SIDS. The original source is available and has been reviewed.
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Niimi, A.J. et al., Octanol/water partition coefficients and bioconcentration factors of chloronitrobenzenes in rainbow trout (salmo gairdneri). Environmental Toxicology and Chemistry 8, 817-823 (1989)
- Reference Type:
- review article or handbook
- Title:
- 1-chloro-4-nitrobenzene
- Author:
- OECD SIDS
- Year:
- 2 002
- Bibliographic source:
- SIDS Initial Assessment Report for SIAM 15, UNEP Publications
Materials and methods
- Principles of method if other than guideline:
- Method: other: 30 fish exposed to 780+/-130 ng TS/L in a flow-through system; aceton used as solvent; samples of 6 fish each analysed at 5,12,20,28 and 36 days of exposure; duplicate water samples taken every 3 or 4 days; GC analysis
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- Test substance: other TS: mono- to pentachloronitrobenzenes
Constituent 1
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
Study design
- Total exposure / uptake duration:
- 36 d
Test conditions
- Test temperature:
- 15 °C
- Nominal and measured concentrations:
- 0.78 µg/l
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- 84 - 112
Any other information on results incl. tables
The BCF were determined for 5 incubation periods: 84 ± 8 for 5 days, 112 ± 23 for 12 days, 96 ± 14 for 20 days, 103 ± 16 for 28 days, and 108 ± 15 for 36 days. The mean BCF was 101 ± 18 with significant differences (p </= 0.05) among the sample intervalls. Since the higher chlorinated nitrobenzenes are possibly dechlorinated by metabolism in fish, a BCF for p-chloronitrobenzene cannot be derived with this test design.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.