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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report Date:
2005

Materials and methods

Principles of method if other than guideline:
An excess of product is shaked with solvent during 24 hours at 20 deg C. After filtration the concentration in solution is determined with spectrometry.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
ethanol
Solubility:
14 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: 2-propanol
Solubility:
5 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: dichloromethane
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: 2-propanone
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
ethyl acetate
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: methyl benzene
Solubility:
25 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: 4-methyl-2-pentanone
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: 2-butanone
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Medium:
other: 1-methoxy-2-propanol
Solubility:
> 20 other: g/100 mL solution
Temp.:
20 °C
Details on results:
no data

Any other information on results incl. tables

Results on solubility in organic solvents:
 Solvent  Solubility in g/100 mL solution
N,N-dimethylacetamide   > 20
 N,N-dimethylformamide  > 20
 acetonitrile  63
 tetrahydrofurane  > 20
 1-methyl-2-pyrrolidinon  55
 acetic acid  > 20
 acetic acid/water (10/90, v/v) (pH = 2.3)  0.091

Applicant's summary and conclusion

Executive summary:

Not applicable