Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Data waiving:
other justification
Justification for data waiving:
the study does not need to be conducted because the physicochemical and toxicological properties suggest no potential for a significant rate of absorption through the skin
Justification for type of information:
Based on molecular profiling, dermal absorption is expected to be (much) lower than oral. Taking together the low acute oral toxicity profile within this group of substances, and the expected low dermal absorption, it is not considered justified from an animal well-fare perspective to perform any additional acute dose toxicity studies.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion