Registration Dossier
Registration Dossier
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EC number: 611-821-4 | CAS number: 5934-29-2
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Nov 2017 - Apr 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- air comparison pycnometer (for solids)
Test material
- Reference substance name:
- L-Histidine Hydrochloride Monohydrate
- EC Number:
- 611-821-4
- Cas Number:
- 5934-29-2
- Molecular formula:
- C6-H9-N3-O2.Cl-H.H2-O
- IUPAC Name:
- L-Histidine Hydrochloride Monohydrate
- Test material form:
- solid: crystalline
- Details on test material:
- - Name: L-Histidine Hydrochloride Monohydrate (HHM)
- Appearance: White crystals or crystalline powder
- Batch: P817T011
- CAS no.: 5934-29-2
- Purity/Composition: 100.1%
- Molecular weight: 209.63 g/mol
- Test item storage: room temperature
- Expiry date: 31 October 2020
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch No.of test material: P817T011
- Expiration date of the lot/batch: 31 October 2020
- Purity: 100.1%
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
Results and discussion
Density
- Key result
- Type:
- relative density
- Density:
- 1.49 g/cm³
- Temp.:
- 20 °C
Any other information on results incl. tables
| Density of the Test Item | |||
| Density [g/cm3] | Test 1 | Test 2 | Mean |
| 1.487 | 1.488 | 1.49 | |
Applicant's summary and conclusion
- Conclusions:
- The density of the test item at 20ºC was 1.49 g/cm3 (1.49 × 103 kg/m3)..
- Executive summary:
A gas comparison stereopycnometer was used for the determination of the density and relative density of L-Histidine Hydrochloride Monohydrate (HHM).
The density of the test item at 20ºC was 1.49 g/cm3 (1.49 × 103 kg/m3).
The relative density was 1.49.
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