Registration Dossier
Registration Dossier
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EC number: 451-530-8 | CAS number: 736150-63-3
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
The acute oral toxicity (LD50) of TS-ED 532 to the Japanese quail was determined to be in excess of 2000 mg/kg bw (the highest level tested). The no observed effect level was 2000 mg/kg bw.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for birds:
- 2 000
Additional information
The acute oral toxicity (LD50) of TS-ED 532 to the Japanese quail was performed in accordance with the method described in the Environmental Protection Agency Pesticide Assessment Guidelines, Subdivision E, Hazard Evaluation: Wildlife & Aquatic Organisms, Series 71 - Avian and Mammalian testing § 71-1 Avian single-dose oral LD50 test (October 1982). This study also included modifications described in the draft EPA guidelines for avian LD50 tests (March 1988) and broadly followed the Draft OPPTS 850.2100 Avian Acute Oral Toxicity Test (1996) where appropriate. Groups of five male and five female adult birds were given a single oral dose of TS-ED 532, by intubation of either 500, 1000, or 2000 mg/kg bw. A similar sized control group was dosed in the same way receiving the vehicle only (corn oil). Birds were observed for 14 days following dosing.
The LD50 of TS-ED 532 to the Japanese quail is in excess of 2000 mg/kg bw (the highest level tested). The no observed effect level was 2000 mg/kg bw.
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