Registration Dossier
Registration Dossier
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EC number: 239-620-3 | CAS number: 15571-48-9
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Magnesium-isopropylate hydrolysis within 1 minute into isopropanol and magnesium hydroxide.
The hydrolysis product isopropanol is readily biodegradable under both aerobic and anaerobic conditions in a wide variety of environmental media including fresh and salt water, sediments and soils, ground water, aquifer material and industrial wastewater. The hydrolysis product magnesium hydroxide is an inorganic substance and as such biodegradation is not relevant. Both hydrolysis products are natural occuring substances. Magnesium-isopropylate and its hydrolysis products isopropanol and magnesium hydroxide are not persistance (P) in the environment.
Magnesium-isopropylate hydrolysis very fast into isopropanol and magnesium hydroxide. The determination of the partitions coefficient is technically not feasible with magnesium-isopropylate and the endpoint is waived.
The half life of magnesium-isopropylate was estimated to be T1/2 < 1 min (Hydrolysis as a Function of pH). In experiments with the chemically very similar substances magnesium methanolate and magnesium ethanolate in buffer solutions (pH4, pH7, pH9) the hydrolysis reaction takes place immediately. Hydrolysis rates of >>= 90% within 1 minute reaction time are observed.
A very low logPow of magnesium-isopropanolate was predicted by QSAR according to EPI Suite 4.11 (KOWWIN v. 1.68) and the data are used as supporting data. The predicted LogPow = -0.17 at 25°C. The LogPow of the hydrolysis product isopropanol is 0.05 at 20°C. For magnesium hydroxide as an inorganic substance no logPow can be determined.
Based on the available data it can be considered that magnesium-isopropylate and its hydrolysis products isopropanol and magnesium hydroxide have a low potential for bioaccumulation and can be considered as not bioaccumulative (B).
Magnesium-isopropylate hydrolyse very fast into isopropanol and magnesium hydroxide. Based on the available data for marine/freshwater organisms the hydrolysis products as natural occuring substances can be considered as safe for the environment. The substance magnesium-isopropylate and its hydrolysis products isopropanol and magnesium hydroxide are not CMR or chronic toxic substances. Therefore magnesium-isopropylate and its hydrolysis products isopropanol and magnesium hydroxide can be consiedered and not toxic (T).
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