Registration Dossier

Administrative data

Key value for chemical safety assessment

Justification for classification or non-classification

Effects on male and female fertility were observed in two intravenous studies in rats.

NOAEL for male fertility: 40 mg / kg / day

NOAEL for female fertility: 20 mg / kg / day

Teratogenic effects in two embryo-fetal toxicity studies (one intravenous and one oral) in rats.