Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-309-2 | CAS number: 57-06-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute and Long-Term Effects of Nine Chemicals on the Japanese Medaka (Oryzias latipes)
- Author:
- G.W.Holcombe, D.A.Benoit, D.E.Hammermeister, E.N.Leonard, R.D.Johnson
- Year:
- 1 995
- Bibliographic source:
- Arch. Environ. Contam. Toxicol. 28, 287-297 (1995)
Materials and methods
- Principles of method if other than guideline:
- 96-hours acute test was conducted with nine organic chemicals, usng the Japanese medaka (Oryzias latipes) as the test organism.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Allyl isothiocyanate
- EC Number:
- 200-309-2
- EC Name:
- Allyl isothiocyanate
- Cas Number:
- 57-06-7
- Molecular formula:
- C4H5NS
- IUPAC Name:
- 3-isothiocyanatoprop-1-ene
- Test material form:
- liquid
Constituent 1
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Oryzias latipes
Study design
- Test type:
- not specified
- Water media type:
- other: Lake Superior water
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- The mean and range for total hardness was 45.8 (38.0-52.0) mg/L as CaCO3 for all tests.
- Test temperature:
- 25 C +/- 1
- pH:
- 7.88 +/- 0.18
Results and discussion
Effect concentrations
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.077 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 96-hours LC50 (Oryzias latipes) value for allyl isothiocyanate was 0.077 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
