Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

Germ cell mutagenicity

Experimental data on the potential of germ cell mutagenicity of the substance are not available.

Predicted data:

- The Toolbox profiler - alert found

- Mutagenicity (Ames test) model (CAESAR) 2.1.13 - NON-Mutagenic - the predicted compound could be out of the Applicability Domain of the model

- Mutagenicity (Ames test) model (SarPy/IRFMN) 1.0.7 - Mutagenic - the predicted compound is outside the Applicability Domain of the model

- Mutagenicity (Ames test) model (ISS) 1.0.2 - Mutagenic - the predicted compound is outside the Applicability Domain of the model

- Mutagenicity (Ames test) model (KNN/Read-Across) 1.0.0 - NON-Mutagen - the predicted compound is into the Applicability Domain of the model  [QSAR VEGA model]

Overall, available information are judged as inconclusive for the classification of the substance.