Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Hazardous to the aquatic environment - acute

Experimental data on aquatic acute toxicity of the substance are not available.

Predicted data are reported below:

- Fish Acute (LC50) Toxicity classification (SarPy/IRFMN) 1.0.2 - Toxic-3 (between 10 and 100 mg/l) - the predicted compound is into the Applicability Domain of the model

- Fish Acute (LC50) Toxicity model (KNN/Read-Across) 1.0.0 - Prediction is 77.03 mg/L - the predicted compound is into the Applicability Domain of the model

- Fish Acute (LC50) Toxicity model (NIC) 1.0.0 - Prediction is 91.86 mg/L - the predicted compound is into the Applicability Domain of the model

- Fathead Minnow LC50 96h (EPA) 1.0.7 - Prediction is 76.06 mg/L - the predicted compound could be out of the Applicability Domain of the model

- Daphnia Magna LC50 48h (EPA) 1.0.7 - Prediction is 0.6205 mg/L - the predicted compound is outside the Applicability Domain of the model [QSAR VEGA model]

- Predicted data for the followings classes (i) anilines, (ii) amides, (iii) neutral organic SAR are between 0.260 and 132,449 mg/L [Ecosar model]

Overall, available information are judged as inconclusive for the classification of the substance.

Hazardous to the aquatic environment - chronic

Experimental data on aquatic chronic toxicity of the substance are not available.

Predicted data are reported below:

- Fish Acute (LC50) Toxicity classification (SarPy/IRFMN) 1.0.2 - Toxic-3 (between 10 and 100 mg/l) - the predicted compound is into the Applicability Domain of the model

- Fish Acute (LC50) Toxicity model (KNN/Read-Across) 1.0.0 - Prediction is 77.03 mg/L - the predicted compound is into the Applicability Domain of the model

- Fish Acute (LC50) Toxicity model (NIC) 1.0.0 - Prediction is 91.86 mg/L - the predicted compound is into the Applicability Domain of the model

- Fathead Minnow LC50 96h (EPA) 1.0.7 - Prediction is 76.06 mg/L - the predicted compound could be out of the Applicability Domain of the model [QSAR VEGA model]

- Log Kow: 1.649 [Ecosar model]

Overall, available information are judged as inconclusive for the classification of the substance.