Potassium; 2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate; iron(3+)

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

February - April 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

GLP compliance:

yes (incl. QA statement)

Remarks:

certificate no.: 17/2017/DPL

Type of method:

capillary method

Decomposition:

yes

Decomp. temp.:

218.7 °C

Preliminary test

At 227.0°C when heated at 10.0 ˚C per minute change in color was observed from yellow to brown at the lower end of the capillary (the beginning of decomposition),  at 250.0 ˚C the level of substance increased. At 260 ˚C change in color to beige and next again to brown was observed.

Final test

The three series of boiling point measurements were performed in the temperature range 217.0 - 400.0 °C. The heating rate was 0.5 °C/min.

In sample number 3 at 217.0 ˚C stratification of tested substance took place, in sample number 2 change the tint to yellowish-brown at 218.1 ˚C was observed, sample number 1 started to change the tint to beige at 221.0 ˚C. At 227.0 ˚C characteristic smell indicating the thermal decomposition of the sample was observed.

Conclusions:

DTPA-FeK (FeDTPA K) decomposes below melting and boiling point under atmospheric pressure of 1000.7 hPa at 218.7 ± 2.1 °C (the average value).
(Methods: EEC A.1 and OECD No. 102; EEC A.2 and OECD No. 103)

Executive summary:

In accordance OECD Guideline 102 and 103, determination of the melting point and boiling point of DTPA-FeK (FeDTPA K) was carried out. The preliminary study and measurements were performed under atmospheric pressure of 1000.7 hPa. The study was carried out in order to determine the melting temperature range for DTPA-FeK (FeDTPA K) (50.0 – 400.0°C).

The three series of boiling point measurements (final test) were performed in the temperature range 217.0 - 400.0 °C. The heating rate was 0.5 °C/min. For all three samples the thermal decomposition was observed. The average value of initial  decomposition temperature for the three samples  of DTPA-FeK (FeDTPA K) is 218,7 ± 2,1 °C.

Description of key information

DTPA-FeK (FeDTPA K) decomposes below melting and boiling point under atmospheric pressure of  1000.7 hPa at 218.7 ± 2.1 °C  (the average value). (Methods: EEC A.1 and OECD No. 102; EEC A.2 and OECD No. 103). The average value of initial  decomposition temperature for the three samples  of DTPA-FeK (FeDTPA K) is 218,7 ± 2,1 °C.