Registration Dossier
Registration Dossier
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EC number: 213-485-0 | CAS number: 957-68-6
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 01, 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study (OECD109) with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- air comparison pycnometer (for solids)
- Key result
- Type:
- relative density
- Density:
- 1.51
- Temp.:
- 20 °C
- Conclusions:
- According to OECD Test Guidelines 109 (1995) and EC 440/2008 Part A. Method A.3., the relative density D420 of the test item 7-Aminocephalosporanic acid at 20 °C ± 0.01 °C (compared to water at 4 °C) is D420 = 1.51.
- Executive summary:
The relative density is 1.51 at 20 °C.
Reference
Two tests with different amounts of the test item were performed to determine the relative density D420at a temperature of 20 °C ±0.01 °C.Table1summarises the results.
Table1: Results of the measurement of the density of the test item
Test No. |
Temperature [°C] |
Test item chamber volume |
Reference chamber volume |
Weight in of test item [g] |
Density [g/cm³]* |
1 |
20 |
Small (25.62 cm³) |
76 (21.35 cm³) |
11.34 |
1.50933 |
2 |
20 |
Small (25.62 cm³) |
76 (21.35 cm³) |
10.96 |
1.50595 |
* The pressurizing-expansion cycles are performed until 5 subsequent volume measurements have a relative standard deviation (RSD) of ≤ 0.02 %.
The mean density of the test item at 20 °C is 1.507677692 g/cm³ (SD = 0.0024, RSD = 0.16 %). The relative density D420is calculated by dividing the density of the test item by the density of water at 4 °C (0.9999750 g/cm³).
The relative density is D420= 1.51.
Description of key information
The relative density is 1.51 at 20 °C.
Key value for chemical safety assessment
- Relative density at 20C:
- 1.51
Additional information
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