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EC number: 206-793-1 | CAS number: 375-73-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Deviations:
- yes
- Remarks:
- one sample per concentration only; octanol:water no variation in volumes tested. Analytics is not substance specific (only titration of acid). Report does not conform with guideline.
- GLP compliance:
- no
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- titration method
- Type:
- Pow
- Partition coefficient:
- 3
- Temp.:
- 23 °C
- pH:
- > 0 - < 0.5
- Remarks on result:
- other: starting concentration between 0.5 and 1 mol/L
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.46
- Temp.:
- 23 °C
- pH:
- 1.7
- Remarks on result:
- other: concentration of aqueous phase before shaking = 0.01 mol/L
- Conclusions:
- The log Kow of PFBS was dermined with shake flask method to be -0.34 at 23°C and pH of 1.7
Reference
Konzentration |
Verteilungskoeffizent |
||
Stammlösung |
organische Phase |
wässrige Phase |
|
mol/l |
mol/l |
mol/l |
Kow |
0,987 |
0,676 |
0,2245 |
3,01 |
0,50 |
0,330 |
0,110 |
3,00 |
0,749 |
0,480 |
0,160 |
3,00 |
|
|
Æ |
3,0 |
Description of key information
The logKow of PFBS was determined as -0.34 in a 0.01 mol/L concentration (pH 1.7) at 23°C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.34
- at the temperature of:
- 23 °C
Additional information
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