Registration Dossier

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Jusqu'à 1971
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract

Data source

Reference
Reference Type:
publication
Title:
Systematic search for a systemic hydatid scolicide. I. In vitro screening of chemicals against the scolices of hydatid cysts (Echinococcus granulosus)
Author:
Frayha GJ , Saheb SE, Dajani RM
Year:
1971
Bibliographic source:
Chemotherapy 16(6):371-9

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Injection intrapéritonéale
GLP compliance:
not specified
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Specific details on test material used for the study:
Non disponible

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
Non disponible

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Details on exposure:
Non disponible
Doses:
Non disponible
No. of animals per sex per dose:
Non disponible
Control animals:
not specified
Details on study design:
Non disponible
Statistics:
Non disponible

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
76 mg/kg bw
Mortality:
Non disponible
Clinical signs:
Non disponible
Body weight:
Non disponible
Gross pathology:
Non disponible
Other findings:
Non disponible

Applicant's summary and conclusion

Conclusions:
Une DL50 de 76 mg/kg de poids corporel pour l'acétylacétonate de fer a été établie chez des souris par voie intrapéritonéale.
Executive summary:

Cette étude a consisté à injecter de l'acétylacétonate de fer à des souris par voie intrapéritonéale. Une DL50 de 76 mg/kg de poids corporel a été établie.