Registration Dossier
Registration Dossier
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EC number: 237-853-5 | CAS number: 14024-18-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Jusqu'à 1971
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
Data source
Reference
- Reference Type:
- publication
- Title:
- Systematic search for a systemic hydatid scolicide. I. In vitro screening of chemicals against the scolices of hydatid cysts (Echinococcus granulosus)
- Author:
- Frayha GJ , Saheb SE, Dajani RM
- Year:
- 1 971
- Bibliographic source:
- Chemotherapy 16(6):371-9
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Injection intrapéritonéale
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- Tris(pentane-2,4-dionato)iron(II)
- EC Number:
- 237-853-5
- EC Name:
- Tris(pentane-2,4-dionato)iron(II)
- Cas Number:
- 14024-18-1
- Molecular formula:
- C15H21FeO6
- IUPAC Name:
- iron(3+) tris(4-oxopent-2-en-2-olate)
- Test material form:
- solid: crystalline
Constituent 1
- Specific details on test material used for the study:
- Non disponible
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- Non disponible
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Details on exposure:
- Non disponible
- Doses:
- Non disponible
- No. of animals per sex per dose:
- Non disponible
- Control animals:
- not specified
- Details on study design:
- Non disponible
- Statistics:
- Non disponible
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 76 mg/kg bw
- Mortality:
- Non disponible
- Clinical signs:
- Non disponible
- Body weight:
- Non disponible
- Gross pathology:
- Non disponible
- Other findings:
- Non disponible
Applicant's summary and conclusion
- Conclusions:
- Une DL50 de 76 mg/kg de poids corporel pour l'acétylacétonate de fer a été établie chez des souris par voie intrapéritonéale.
- Executive summary:
Cette étude a consisté à injecter de l'acétylacétonate de fer à des souris par voie intrapéritonéale. Une DL50 de 76 mg/kg de poids corporel a été établie.
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