Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
respiratory sensitisation
Remarks:
other: Experience at the workplace.
Type of information:
other: Experience at the workplace.
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Experience at the workplace.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Experience at the workplace.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EC Number:
261-491-7
EC Name:
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cas Number:
58909-56-1
Molecular formula:
C12H13N5O5S2
IUPAC Name:
7-amino-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Test animals

Species:
human

Results and discussion

Results:
7-ACT was recognised as being a respiratory sensitizer at the workplace.

Applicant's summary and conclusion

Interpretation of results:
sensitising
Conclusions:
7-ACT was recognised as being a respiratory sensitizer at the workplace.
Executive summary:

7-ACT was recognised as being a respiratory sensitizer at the workplace.

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