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EC number: 948-065-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
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- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20-02-2018 to 26-07-2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Guideline study performed under GLP. All relevant validity criteria were met with acceptable deviations that yield scientifically plausible results.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: isothermal thermogravimetry
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- <= 7.6 Pa
- Remarks on result:
- other: weight losses of the test item were compared with the results of naphthalene at 50°C and 60°C
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- <= 12 Pa
- Remarks on result:
- other: weight losses of the test item were compared with the results of naphthalene at 50°C and 60°C
- Conclusions:
- The vapour pressure of the test item was determined to be < 7.6 Pa at 20°C (293K) and < 12 Pa at 25°C (298K), respectively.
- Executive summary:
The vapour pressure was determined using the thermogravimetric effusion method in OECD TG 104, EU Method A.4 and US EPA OPPTS 830.7950 under GLP. The vapour pressure of the test item was determined to be: < 7.6 Pa (5.7 x10^-2 mmHg) at 20°C (293K) and < 12 Pa (8.6 x10^-2 mmHg) at 25°C (298K), respectively.
Applicant assessment indicates: Reported literature values for naphthalene indicate: Vapour Pressure = 7.2 Pa at 20 °C and 10.5 Pa at 25 °C. Reference: DeKruif C.G. et al., (1982): J. Chem. Thermodynamics 13, 1081-1086. Published literature values for 2-hydroxyethyl methacrylate, (ECHA, 2018) indicate a range of Vapour Pressures of 8.0 Pa at 20 °C and 13 Pa at 25 °C. For the test item the quoted ranges of vapour pressure are scientifically plausible limit values. Comparable with a measured reference substance (naphthalene) and information concerning residual starting material (2-hydroxyethyl methacrylate).
Reference
The results of the isothermal TGA analysis for the test item and the vapour pressure at 20°C and 25°C are given below:
Table 1: Results of the isothermal TGA analysis
Temperature [°C] |
Weight loss [µg/min] |
50 |
7.86543 |
60 |
2.78110 |
70 |
6.15794 |
80 |
12.8712 |
In the range of 50°C and 80°C a log p versus 1/T curve for the test item could not be determined since the coefficient of correlation (r) was < 0.99 (reported in the full study report).
Since no accurate vapour pressure could be calculated from the obtained results the weight losses of the test item were compared with the results of naphthalene at 50°C and 60°C. According to this the vapour pressure of the test item was determined to be lower than that of naphthalene
Table 2: Vapour pressure of the test item
|
20°C |
25°C |
||
|
[Pa] |
[mm Hg] |
[Pa] |
[mm Hg] |
Test item |
< 7.6 |
< 5.7´10-2 |
< 12 |
< 8.6´10-2 |
Applicant assessment indicates: Reported literature values for naphthalene indicate: Vapour Pressure = 7.2 Pa at 20 °C and 10.5 Pa at 25 °C. Reference: DeKruif C.G. et al., (1982): J. Chem. Thermodynamics 13, 1081-1086
Description of key information
Vapour Pressure: < 7.6 Pa at 20 °C and < 12 Pa at 25 °C, OECD TG 104 - thermogravimetric effusion method, 2018
Key value for chemical safety assessment
- Vapour pressure:
- 12 Pa
- at the temperature of:
- 25 °C
Additional information
Key study : OECD TG 104, 2018 : The vapour pressure was determined using the thermogravimetric effusion method in OECD TG 104, EU Method A.4 and US EPA OPPTS 830.7950 under GLP. The vapour pressure of the test item was determined to be: < 7.6 Pa (5.7 x10^-2 mmHg) at 20°C (293K) and < 12 Pa (8.6 x10^-2 mmHg) at 25°C (298K), respectively.
Applicant assessment indicates: Reported literature values for naphthalene indicate: Vapour Pressure = 7.2 Pa at 20 °C and 10.5 Pa at 25 °C. Reference: DeKruif C.G. et al., (1982): J. Chem. Thermodynamics 13, 1081-1086. Published literature values for 2-hydroxyethyl methacrylate, (ECHA, 2018) indicate a range of Vapour Pressures of 8.0 Pa at 20 °C and 13 Pa at 25 °C. For the test item the quoted ranges of vapour pressure are scientifically plausible limit values. Comparable with a measured reference substance (naphthalene) and information concerning residual starting material (2-hydroxyethyl methacrylate).
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