Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21.11.- 22.11.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
Adopted 27 July 1995
Deviations:
yes
Remarks:
See Any other information
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Version / remarks:
Council regulation (EC) No 440/2008
Deviations:
yes
Remarks:
See Any other information
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
-0.92
Temp.:
23 °C
pH:
4.62

A stock solution of the test substance should be prepared in n-octanol pre-saturated with water. Because of a low solubility of the test substance in this medium, the stock solution was prepared in water pre-saturated with n-octanol. This deviation has no effect on the determination of log Pow of the test substance.

There were no other deviations from study plan or guidelines during the study

Conclusions:
Partition coefficient (log P) of the test substance 5-Aminotetrazole determined by shake-flask method is:
log Pow = -0.92 ± 0.02 (pH 4.62, 23°C)
Executive summary:

The partition coefficient of the test substance 5 -Aminotetrazole was determined.

For determination of partition coefficient was used the shake-flask method.

The test was performed according to the shake-flask method (OECD Test Guideline 107, Partition Coefficient (n-octanol/water): Shake Flask Method, Adopted 27 July 1995).

Partition coefficient (log P) of the test substance 5-Aminotetrazole determined by shake-flask method is:

log Pow = -0.92 ± 0.02 (pH 4.62, 23°C)  

Description of key information

The test was performed according to the shake-flask method (OECD Test Guideline 107, Partition Coefficient (n-octanol/water): Shake Flask Method, Adopted 27 July 1995).

Partition coefficient (log P) of the test substance 5-Aminotetrazole determined by shake-flask method is:

log Pow = -0.92 ± 0.02 (pH 4.62, 23°C)

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.92
at the temperature of:
23 °C

Additional information