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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08 Apr - 09 May 1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Basic data given. Data on analytical purity, guideline and animal husbandry are missing.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report date:
1994

Materials and methods

Principles of method if other than guideline:
The LD50 of the test substance was determined by administering 5 female mice 2000 mg/kg bw orally. The animals were observed for mortality and signs of toxicity for 6 days, and the body weight was determined at the start and end of the study period.
GLP compliance:
no
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Decyl oleate
EC Number:
222-981-6
EC Name:
Decyl oleate
Cas Number:
3687-46-5
Molecular formula:
C28H54O2
IUPAC Name:
decyl octadec-9-enoate

Test animals

Species:
mouse
Strain:
other: NMRI EOPS
Sex:
female
Details on test animals or test system and environmental conditions:
TEST ANIMALS
- Weight at study initiation: 19-21 g

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
2000 mg/kg bw
No. of animals per sex per dose:
5 females
Control animals:
no
Details on study design:
- Duration of observation period following administration: 6 days
- Necropsy of survivors performed: no
- Other examinations performed: mortality, clinical signs, body weight

Results and discussion

Effect levels
Key result
Sex:
female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Mortality:
There was no mortality during the study period.
Clinical signs:
other: No signs of toxicity were observed during the study period.

Applicant's summary and conclusion

Interpretation of results:
other: CLP/EU GHS criteria not met, no classification required according to Regulation (EC) No 1272/2008.

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