Fatty acids, C16, C18 and C18-unsaturated, C12-15 alcohol (linear and branched), esters

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08 Apr - 09 May 1994

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

Basic data given. Data on analytical purity, guideline and animal husbandry are missing.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1994

Report date:

1994

Materials and methods

Principles of method if other than guideline:

The LD50 of the test substance was determined by administering 5 female mice 2000 mg/kg bw orally. The animals were observed for mortality and signs of toxicity for 6 days, and the body weight was determined at the start and end of the study period.

GLP compliance:

no

Test type:

standard acute method

Limit test:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Decyl oleate

EC Number:

222-981-6

EC Name:

Decyl oleate

Cas Number:

3687-46-5

Molecular formula:

C28H54O2

IUPAC Name:

decyl octadec-9-enoate

Test animals

Species:

mouse

Strain:

other: NMRI EOPS

Sex:

female

Details on test animals or test system and environmental conditions:

TEST ANIMALS
- Weight at study initiation: 19-21 g

Administration / exposure

Route of administration:

oral: unspecified

Vehicle:

not specified

Doses:

2000 mg/kg bw

No. of animals per sex per dose:

5 females

Control animals:

no

Details on study design:

- Duration of observation period following administration: 6 days
- Necropsy of survivors performed: no
- Other examinations performed: mortality, clinical signs, body weight

Results and discussion

Effect levels

Key result

Sex:

female

Dose descriptor:

LD50

Effect level:

> 2 000 mg/kg bw

Based on:

test mat.

Mortality:

There was no mortality during the study period.

Clinical signs:

other: No signs of toxicity were observed during the study period.

Applicant's summary and conclusion

Interpretation of results:

other: CLP/EU GHS criteria not met, no classification required according to Regulation (EC) No 1272/2008.