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EC number: 947-849-1
CAS number: -
No effects up to the limit of water solubility (OECD 201, D.
There is no study available, in which the toxicity of Fatty acids,
C16, C18 and C18-unsaturated, C12-15 alcohol (linear and branched),
esters to aquatic algae was assessed. Therefore, read-across to the
structurally and chemically closely related source substance Dodecyl
oleate (CAS 36078-10-1) was performed in accordance with Regulation (EC)
No 1907/2006 Annex XI, section 1.5 in order to fulfill the data
requirements for this substance. The source substance is characterized
by similar fatty acid chain lengths and alcohol components as the target
substance and is therefore considered a suitable representative for the
assessment of the toxicity of the target substance to aquatic algae. A
detailed read-across justification in provided in IUCLID section 13.
The available study with the source substance Dodecyl oleate was
conducted according to OECD guideline 201 in compliance with GLP. The
green algae Desmodesmus subspicatus was exposed to five Water
Accommodated Fractions with nominal loading levels ranging from 3.57 to
100 mg/L for 72 h. The measured test item concentrations in the test
solutions were below the limit of quantification (< 0.005 mg/L). After
72 h, no effects on growth rates and yield were recorded. Thus, it is
concluded that Dodecyl oleate does not cause toxic effects to aquatic
algae up to the limit of water solubility.
Based on the high degree of structural and chemical similarity
between the target and the selected source substance, the target
substance is expected to exhibit a similar ecotoxicological profile as
the source substance. Therefore, it can be concluded that the target
substance Fatty acids, C16, C18 and C18-unsaturated, C12-15 alcohol
(linear and branched), esters does not cause toxic effects to aquatic
algae up to its limit of water solubility (< 6.57 µg/L at 20 °C, pH 6.3,
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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