Registration Dossier

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

In the absence of adequate chronic aquatic toxicity information from all three trophic levels, the classification was based on the lowest of the short-term aquatic toxicity values from the three trophic levels (48-h EC50 = 43% saturated solution in daphnids). Although analytical monitoring was conducted in the study, the substance was reported below the limit of quantitation (0.052 mg/L) in all test solutions for which chemical analysis was performed. The limit of quantitation was slightly below the water solubility of the substance of 0.05323 mg/L. Therefore, the toxicity of the substance was based upon the percent saturation of the predicted water solubility of the substance (i.e., 43% of 0.5323 mg/L), resulting in an estimated EC50 of 0.023 mg/L. This estimated EC50 value is uncertain (as it is based on neither directly measured or nominal concentrations nor an experimentally-determined water solubility); therefore, use of this value in environmental classification is highly precautionary. The substance was predicted to be not readily biodegradable through QSAR modeling. The octanol-water partition coefficient was experimentally determined to be log Kow > 6.5 and predicted by QSAR modelling to be log Kow= 6.53. Therefore, the substance was assigned a classification of Category Acute 1 and Category Chronic 1 for hazards to the aquatic environment, each with an M-factor of 10.