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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 - 22 January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Batch No. of test material: FH20170302
- Manufacturing date of the batch: March 2017
- Expiration date of the batch: March 2019
- Purity: 98.65%
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.7
Temp.:
25 °C
pH:
7.5
Details on results:
The results of the test item are as follows:

- Average Log Pow: 1.699
- Agreement [S1-S2]: 0.0003
Conclusions:
The partition coefficient (n-octanol/water) of the test item, Formononetin was determined according to OECD 117. The partition coefficient (n-octanol/water) proved to be 1.70.

Description of key information

The partition coefficient (n-octanol/water) of the test item, Formononetin was determined according to OECD 117. The partition coefficient (n-octanol/water) proved to be 1.70.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.7
at the temperature of:
25 °C

Additional information