Registration Dossier
Registration Dossier
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EC number: 608-818-5 | CAS number: 32997-86-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-06-12 to 2018-07-30
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The preliminary test, miscibility test with visual inspection was performed.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The preliminary test, miscibility test with visual inspection was performed.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The preliminary test, miscibility test with visual inspection was performed.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: miscible test with visual inspection
- Key result
- Remarks on result:
- completely miscible
- Conclusions:
- The test item is completely miscible in water at room temperature.
- Executive summary:
A study according to OECD TG 105, EU Method A.6 and OPPTS 830.7840 was conducted to determine the water solubility of the test item. The test item was expected to be miscible in water, therefore, a preliminary test with visual inspection was performed. Three ratios test item : water were prepared – 1:9, 1:1 and 9:1. After preparation of the test solutions it was visually determined if precipitation was formed. No precipitation was observed in any of the tested ratios. In conclusion, the test item is considered to be completely miscible in water at room temperature.
Reference
No precipitations were observed by visual inspection in any of the prepared solutions. Hence, it is considered that the test item is completely miscible with milli-Q water at room temperature.
Table 1. Miscibility test
Ratios |
Ratios Volume |
Visual Observation |
Test item : Milli Q water (1: 9) |
10 mL : 90 mL |
Miscible |
Test item : Milli Q water (1: 1) |
50 mL : 50 mL |
Miscible |
Test item : Milli Q water (9: 1) |
90 mL : 10 mL |
Miscible |
Description of key information
The test item is completely miscible in water at room temperature.
Key value for chemical safety assessment
Additional information
A study according to OECD TG 105, EU Method A.6 and OPPTS 830.7840 was conducted to determine the water solubility of the test item. The test item was expected to be miscible in water, therefore, a preliminary test with visual inspection was performed. Three ratios test item : water were prepared – 1:9, 1:1 and 9:1. After preparation of the test solutions it was visually determined if precipitation was formed. No precipitation was observed in any of the tested ratios. In conclusion, the test item is considered to be completely miscible in water at room temperature.
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