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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 August 2016 - 25 October 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23. March 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
24 August 2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
August 1996
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
LAUS GmbH, Auf der Schafweide 20, 67489 Kirrweiler, Germany
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Remarks on result:
other: calculated from the regression equation
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Remarks on result:
other: calculated from the regression equation

The measured values for temperature and vapour pressure were evaluated as follows:

 Parameter  T  Mean P 1/T  Log P
 Unit  K  Pa 1/K Log Pa
 Value  393.2 2.98E-03 2.5432E-03 -2.5251
408.2 5.52E-03 2.4498E-03 -2.2581
 423.2  9.33E-03 2.3629E-03 -2.0299

The graph with log P vs. 1/T was plotted. Since the values were correlated by a linear relation, the data could be fitted by linear regression.

 Parameter  Value
 Slope -2748.0
 Intercept 4.4671
 Correlation Coefficient r -0.9997
 Coefficient of Determination r2  0.9994

The following vapour pressures were determined experimentally and considered as valid (mean and standard deviation given):

T  T  Mean P  Stand.Dev.P  RSD P
°C  K  Pa  Pa  %
120°C 393.2 2.98E-03 7.39E-05 2.5%
135°C  408.2 5.52E-03  2.57E-04  4.7%
 150°C 423.2 9.33E-03  3.97E-04 4.3% 

In this table, E-0X represents multiplication with 10-x. Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation

Conclusions:
The vapour pressure of the test item was calculated to be 1.24E-5 Pa at 20°C and 1.78E-5 Pa at 25°C respectively.
Executive summary:

A study was conducted according to OECD TG 104, EU method A.4 and EPA OPPTS 830.7950 to determine the vapour pressure of the test item at nine different temperatures (30, 45, 60, 75, 90, 105, 120, 135 and 150°C) using the effusion method (Knudsen cell). Experiment 1 - 6 (nominal temperature 30- 105 °C) yielded no relevant or reproducible weight loss. Three experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good reproducibility, giving relative standard deviations of less than 5 % and very good correlation. Therefore, the result of the test can be considered valid. The vapour pressure of the test item was calculated to be 1.24E-5 Pa at 20°C and 1.78E-5 Pa at 25°C respectively.

 

Description of key information

The vapour pressure of the test item was calculated to be 1.24E-5 Pa at 20 °C and 1.78E-5 Pa at 25 °C respectively.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

A study was conducted according to OECD TG 104, EU method A.4 and EPA OPPTS 830.7950 to determine the vapour pressure of the test item at nine different temperatures (30, 45, 60, 75, 90, 105, 120, 135 and 150°C) using the effusion method (Knudsen cell). Experiment 1 - 6 (nominal temperature 30- 105 °C) yielded no relevant or reproducible weight loss. Three experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good reproducibility, giving relative standard deviations of less than 5 % and very good correlation. Therefore, the result of the test can be considered valid. The vapour pressure of the test item was calculated to be 1.24E-5 Pa at 20 °C and 1.78E-5 Pa at 25 °C, respectively.