Registration Dossier
Registration Dossier
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EC number: 229-695-0 | CAS number: 6658-48-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1977
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- 1 page study summary
Data source
Reference
- Reference Type:
- other: 1 page study summary
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: no guideline specified on the 1 page study summary
- GLP compliance:
- no
- Remarks:
- Conducted prior to the GLP guidelines
- Limit test:
- yes
Test material
- Reference substance name:
- 3-(p-cumenyl)-2-methylpropionaldehyde
- EC Number:
- 229-695-0
- EC Name:
- 3-(p-cumenyl)-2-methylpropionaldehyde
- Cas Number:
- 6658-48-6
- Molecular formula:
- C14H20O
- IUPAC Name:
- 3-(4-isopropylphenyl)-2-methylpropanal
Constituent 1
- Specific details on test material used for the study:
- Sample marking: 77-413, Rhodial
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- 5'000 mg/Kg BW
- No. of animals per sex per dose:
- 1 dose per animals
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- 1 death occurred on day 1
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The LD50 of Silvial in rabbits has been determined to be above 5'000 mg/Kg bw. Hence the GHS criteria are not met for classification.
- Executive summary:
The LD50 of Silvial in rabbits has been determined to be above 5'000 mg/Kg bw. Hence the GHS criteria are not met for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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