3-(p-cumenyl)-2-methylpropionaldehyde

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 23, 2013 to February 10, 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)

Qualifier:

according to guideline

Guideline:

EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)

Qualifier:

according to guideline

Guideline:

EPA OPPTS 835.3110 (Ready Biodegradability)

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

Name (as stated in the report): Silvial
Batch No.: VE00288629
Expiration date: May 27, 2014

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, domestic (adaptation not specified)

Details on inoculum:

Fresh activated sludge from a biological waste water treatment plant treating predominantly domestic sewage (Bois-de-Bay, Satigny, Switzerland) was used.
The sludge is collected in the morning, washed three times in the mineral medium (by centrifuging at 1000 g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day.

Duration of test (contact time):

69 d

Initial conc.:

30 mg/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

O2 consumption

Reference substance:

other: Sodium benzoate (Fluka, Buchs, Switzerland, Art. No. 71300), purity : min. 99.0%.

Key result

Parameter:

% degradation (O2 consumption)

Value:

76

Sampling time:

28 d

Remarks on result:

other: The 10-day window criterion is also fulfilled (16% biodegradation on day 14 and 67% on day 24).

Details on results:

The 10-day window criterion is also fulfilled (16% biodegradation on day 14 and 67% on day 24). Silvial did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration.

Degradation of sodium benzoate exceeded 40% after 7 days and 65% after 14 days: the activity of the inoculum was thus verified (validity criterion).The repeatability validity criterion (not more than 20% difference between replicates) is fulfilled at the end of the 28 day period. Therefore, the test is considered valid.

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

Silvial undergoes 76% biodegradation after 28 days in the test conditions. The 10-day window criterion is also fulfilled (16% biodegradation on day 14 and 67% on day 24).
Silvial did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration.
Thus, Silvial should be regarded as readily biodegradable according to this test.

Executive summary:

The Ready Biodegradability of Silvial was determined by the Manometric Respirometry Test.

Silvial undergoes 76% biodegradation after 28 days in the test conditions.The 10-day window criterion is also fulfilled (16% biodegradation on day 14 and 67% on day 24).

Silvial did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration. Thus, Silvial should be regarded as readily biodegradable according to this test.

 

Description of key information

The Ready Biodegradability of Silvial was determined by the Manometric Respirometry Test.

Silvial undergoes 76% biodegradation after 28 days in the test conditions. The 10-day window criterion is also fulfilled (16% biodegradation on day 14 and 67% on day 24).

Silvial did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration of 30 mg/L.

Thus, Silvial should be regarded as readily biodegradable according to this test.

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Type of water:

freshwater