Registration Dossier
Registration Dossier
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EC number: 480-880-4 | CAS number: 608-23-1
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Boundary composition
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- Boundary composition
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The submission substance fulfils the P- and T-criterion (not degradable according to biodegradation screening test; classified as STOT RE Cat. 2), but does not fulfil the vB/B criterion (BCF < 2000): Reliable QSAR based data on BCF for fish (QMRF demonstrating validity of QSAR model; QPRF demonstrating (1) applicability of QSAR model on submission substance, (2) reliability of the prediction, as well as (3) relevance of the prediction for the regulatory purpose) allow for a safe conclusion that the submission substance is not bioaccumulative (BCF 141 L/kg whole body wet weight; worst case BCF implying maximum underestimation from 14 similar compounds: 269 L/kg whole body wet weight). This conclusion is confirmed by two relevant supporting models based on very different methodology.
Therefore, the submission substance is assessed to be not PBT / vPvB acc. to Annex XIII of Regulation (EC) No 1907/2006.
- Likely routes of exposure:
Exposure considerations not required as the substance is not PBT / vPvB.
Reference
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