Registration Dossier
Registration Dossier
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EC number: 216-208-1 | CAS number: 1528-49-0
Acute Toxicity: dermal
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Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Test material form:
- liquid
- Details on test material:
- Manufactured by Daihachi Chemical Industry Co., Lot. No. 60601, purity ≥ 99.0%. Liquid, pale yellow, transparent oil-soluble. Molecular weight 546.87, Freezing point -30 ° C., boiling point 430 ° C.
Constituent 1
Test animals
- Species:
- rabbit
Administration / exposure
- Type of coverage:
- occlusive
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 mL/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: greater than approx. 2000 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute dermal LD50 in rabbits is reported to be > 2.0 ml/kg bw, approximately equivalent to 2000 mg/kg bw.
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