Fenuron

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Principles of method if other than guideline:

Crangon crangon used as test organism
Test performed in filtered sea-water
Test temperature 15°C
semi-static exposure, daily water renewal
Exposure for about 110 hours, tanks were inspected frequently and EC50s were calculated

GLP compliance:

no

Analytical monitoring:

no

Test organisms (species):

Crangon crangon

Test type:

semi-static

Water media type:

saltwater

Total exposure duration:

110 h

Remarks on exposure duration:

Total test duration estimated from Fig. 1, only result for 48 hours extrapolated

Test temperature:

15°C

Details on test conditions:

TEST SYSTEM
- Test vessel: Perspex tanks
- Type (delete if not applicable): open / closed
- Material, size, headspace, fill volume:
- Aeration: yes, gentle aeration
- Renewal rate of test solution (frequency): every 24 hours
- No. of organisms per vessel: not reported
- No. of vessels per concentration (replicates): not reported
- No. of vessels per control (replicates): not reported

TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: natural filtered seawater

OTHER TEST CONDITIONS
- Photoperiod: not reported
- Light intensity:not reported

EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : mortality, "tanks were inspected frequently". The LC50 was calculated for each observation interval and the 48 hour LC50 was determined by regression analysis.

RANGE-FINDING STUDY
- Results used to determine the conditions for the definitive study: A range-finding test was performed, but the details were not reported.

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

600 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Conclusions:

48-h LC50 Crangon crangon: 600 mg/L

Description of key information

EC50: 600 mg/L

Key value for chemical safety assessment

Marine water invertebrates

Marine water invertebrates

Effect concentration:

600 mg/L

Additional information

Data from three (marine) invertebrates are available. In a test with (Crangon crangon) the 48 -hour EC50 was experimentally determined to be 600 mg/L. The data demonstrate that invertebrates are less sensitive when compared to algae. Two further limits test showed that further invertebrates were also not sensitive at 1 and 2 mg/L. Hence further testing was considered not necessary.