Registration Dossier

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
The deviation of the temperature during the test was higher than ±0.5 °C. The highest deviation was 2.4 °C. This deviation does not have any effect on the overall study conclusions.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
The deviation of the temperature during the test was higher than ±0.5 °C. The highest deviation was 2.4 °C. This deviation does not have any effect on the overall study conclusions.
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Key result
Water solubility:
< 0.2 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
> 7.79 - < 8.51

Results of the determination of Solvent Blue 79B concentrations

Analytical occasion / Time Period

Flow rate
(ml / hour)

Measured concentration ofSolvent Blue 79B(mg/L)

20 March 2018 / 21 hours

~ 12.5

not detected

pH=8.15

21 March 2018 / 45 hours

not detected

pH=8.00

22 March 2018 / 69 hours

not detected

pH=8.38

23 March 2018 / 93 hours

not detected

pH=8.51

26 March 2018 / 163 hours

not detected

pH =8.38

Mean

 

not detected

20 March 2018 / 21 hours

~ 25

not detected

pH=7.87

21 March 2018 / 45 hours

not detected

pH=7.79

22 March 2018 / 69 hours

not detected

pH=8.18

23 March 2018 / 93 hours

not detected

pH=8.26

26 March 2018 / 163 hours

not detected

pH=8.12

Mean

 

not detected

Mean of the two test

 

 

not detected

Conclusions:
The water solubility of Solvent Blue 79B was determined to be less than the quantitation limit (0.2 mg/L after dilution) using the column elution method and HPLC for analysis.
Executive summary:

The Column Elution method, according to OECD 105 was used to evaluate the water solubility of Solvent Blue 79B. HPLC was used as the method for analysis. Solvent Blue 79B was not detected in any of the analysed solutions, therefore the water solubility can be concluded to be less than the LOQ of the method (0.2mg/L)

Description of key information

The water solubility of Solvent Blue 79B was determined using the column elution method. No Solvent Blue 79 B could be detected in any of the test solutions therefore the solubility was determined to be less than the quantitation limit (0.2 mg/L after dilution) at 20 °C ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:
0.2 mg/L
at the temperature of:
20 °C

Additional information

Categories Display