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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.55
Temp.:
25 °C
pH:
7.5
Conclusions:
The partition coefficient (n-octanol/water) of the test item was determined according to “OECD 117-Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method”. The partition coefficient (n-octanol/water) of test item “DIRECT YELLOW 147”, as weighted average, proved to be 1.55
Executive summary:

Log Pow = 1.55 (weighted average)

Description of key information

The partition coefficient (n-octanol/water) of the test item was determined according to “OECD 117-Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method”. The partition coefficient (n-octanol/water) of the substance proved to be 1.55 (weighted average).

Key value for chemical safety assessment

Log Kow (Log Pow):
1.55
at the temperature of:
25 °C

Additional information