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Physical & Chemical properties

Partition coefficient

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Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 Feb 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Reason / purpose for cross-reference:
reference to same study
Qualifier:
no guideline followed
Principles of method if other than guideline:
The water solubility and octanol solubiltiy of Isomalt were determined separately.
Type of method:
calculation method (fragments)
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
>= -3.9 - <= -3.7
Temp.:
20 °C
Remarks on result:
other: pH not determined

Results

 

Isomalt ST LIMS: 201716921

Solubility in water (saturated with 1-octanol) [g/L]

342

326

Solubility in 1-octanol (saturated with water) [g/L]

0.07

0.04

Partition coefficient

-3.9 to -3.7

The partition coefficient of the examined samples of Isomalt ST is in the range -3.9 to -3.7.

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 Feb 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Reason / purpose for cross-reference:
reference to same study
Qualifier:
no guideline followed
Principles of method if other than guideline:
The water solubility and octanol solubiltiy of Isomalt were determined separately.
Type of method:
calculation method (fragments)
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
>= -4.2 - <= -4.1
Temp.:
20 °C
Remarks on result:
other: pH not determined

Results

 

Isomalt GS LIMS: 201716922

Solubility in water (saturated with 1-octanol) [g/L]

507

499

Solubility in 1-octanol (saturated with water) [g/L]

0.04

0.03

Partition coefficient

-4.2 to -4.1

The partition coefficient of the examined samples of Isomalt GS is in the range -4.2 to -4.1.

Description of key information

The partition coefficient of the examined samples of Isomalt ST and Isomalt GS is in the range -4.2 to -3.7 (HPLC)

Key value for chemical safety assessment

Additional information