Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Trimethylamine N-oxide is a white solid powder with a bulk density of 1.16 g/cm³ at 22 °C and a MMAD of 414.329 µm and a D10 of 161.713 µm. It has a melting point of 100 °C and a boiling point of 158 °C at 1013 hPa.  The measured vapour pressure is 23.5 Pa at 20 °C.  Trimethylamine N-oxide is very water soluble with a measured water solubility of 793 g/L and a corresponding measured log Pow of -2.79.


Trimethylamine N-oxide is not considered as a pyrophoric solid nor a flammable solid.  Additionally, trimethylamine N-oxide is not considered to possess explosive (thermal sensitivity) or oxidizing properties.

Additional information