Registration Dossier
Registration Dossier
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EC number: 237-280-0 | CAS number: 13718-59-7
Toxicity to other above-ground organisms
Administrative data
Link to relevant study record(s)
Description of key information
Several reliable studies (Klimisch 2) were found on toxic effect of Se. The information is used as supporting information in the secondary poisoning assessment of Se-enriched diets (selenium applied as seleno-DL-methionine) on mammals and reptiles.
Key value for chemical safety assessment
Additional information
No significant effects were detected on the mortality, growth and egg production ofLamprophis fuliginosus(brown house snake) at 23 mg Se/kg food (dry mass; Hopkins et al., 2004) or on mortality and growth of the lizardSceloporus occidentalisat 14.7 mg Se/kg food (dry mass; Hopkins et al., 2005).
Additionally, data on dietary toxicity for eight mammal species based on food naturally enriched in Se or amended with various Se-compounds. Reported NOECoral values for growth, reproduction and mortality vary between 1 and 15 mg Se/kg food.
It should be noted that US EPA (2007) identified a large amount of additional studies, with NOEC-values up to 300 mg Se/kg diet. These studies were not all screened for their reliability because no values below the critical NOECoral for birds (1 mg Se/kg food) were reported.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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