Registration Dossier
Registration Dossier
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EC number: 200-796-1 | CAS number: 73-24-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Classification related data
Biodegradability
In a Manometric Respirometry Test according to OECD TG 301 F the test item was found to be readily biodegradable by OECD criteria (99% biodegradation after 28 days).
Partition coefficient
The partition coefficient of the test item Adenine was determined by means of the shake-flask-method to be log Pow = -0.1 at 22 °C (pH 6.5 – 6.8).
Aquatic short-term (acute) toxicity
48-h EC50 (Daphnia magna): > 100 mg/L (nominal)
72-h ErC50 (Raphidocelis subcapitata): 4.33 mg/L (nominal)
Aquatic long-term (chronic) toxicity
72-h ErC10 (Raphidocelis subcapitata): 2.82 mg/L (nominal)
Classification according to CLP
The available data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. The test substance was found to be readily biodegradable and the log Pow was calculated to be -0.1 at 20 °C. Raphidocelis subcapitata was the most sensitive species in aquatic tests, resulting in a 72-h ErC50 of 4.33 mg/L. The long-term endpoint (72-h EC10 for algae) was determined to be 2.82 mg/L. Based on these results, the substance is neither classified for short term (acute) toxicity nor for long-term (chronic) aquatic toxicity according to Regulation (EC) No 1272/2008 (CLP) as amended for the eleventh time in Commission Regulation (EU) 2018/669.
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