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EC number: 947-842-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Justification is provided in the separate statement.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 62.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Conclusions:
- No study is available on The test item. Two studies from supporting substance (structural analogue or surrogate) are available.
In this static limit test according OECD 203 the test item Sodium-N-cocoyl glycinate (a.i content of solution 29.8% ww) did not cause any effects to zebrafish after 96h when tested with a nominal concentration of 100 mg/L (29.8 mg/L a.i.). LC0 and NOEC are 100 mg/L (29.8 mg/L a.i.). LC100 is > 100 mg/L (> 29.8 mg/L a.i.).
In a static test according OECD 203 the test item Sodium N-octoyl glutamate the LC50 of the test item was found to be 150 mg/L test item or 62.4 mg/L a.i. - Executive summary:
No study is available on The test item. Two studies from supporting substance (structural analogue or surrogate) are available.
In this static limit test according OECD 203 the test item Sodium-N-cocoyl glycinate (a.i content of solution 29.8% ww) did not cause any effects to zebrafish after 96h when tested with a nominal concentration of 100 mg/L (29.8 mg/L a.i.). LC0 and NOEC are 100 mg/L (29.8 mg/L a.i.). LC100 is > 100 mg/L (> 29.8 mg/L a.i.).
In a static test according OECD 203 the test item Sodium N-octoyl glutamate the LC50 of the test item was found to be 150 mg/L test item or 62.4 mg/L a.i.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1990-01-22 to 1990-03-05
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: The test substances was directly added to the test vessels. - Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- TEST ORGANISM
- Common name: orfe
- Source: Fish farm Eggers, Hohenwestedt
- Age at study initiation: approx. 4 weeks
- Corpulence factor: 0.8 - 1.1 g/cm^3
- Feeding during test: none
ACCLIMATION
- Acclimation period: For at least 7 days
- Acclimation conditions: same dilution water
- Type and amount of food: Pitti Floxi-Flocken Alleinfutter für Zierfische
- Feeding frequency: twice a week - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 15 ± 3° dH (total hardness)
- Test temperature:
- 20 ± 0.5 °C
- pH:
- 7.3 - 8.2
- Dissolved oxygen:
- 4.4 - 8.6 mg/L
- Nominal and measured concentrations:
- Nominal concentration: 150, 175, 190 and 200 mg/L (based on test material)
Nominal concentration: 48, 56, 60.8 and 64 mg/L (based on active matter) - Details on test conditions:
- TEST SYSTEM
- Test vessel: tanks (L 28.5 cm / W 21.0 cm / H 24.0 cm)
- Material: glass; Fill volume: 15 L
- Aeration: weak aeration during test period
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- Biomass loading rate: 3.7 fish/L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: mixture of drinking water and deionized water
- Ca/mg ratio: 4:1
- Culture medium different from test medium: no
- Intervals of water quality measurement: Oxygen concentration and pH were measured after 24, 48, 72 and 96 h test duration.
EFFECT PARAMETERS MEASURED: Mortality was recorded after 24, 48, 72 and 96 h test duration.
TEST CONCENTRATIONS
- Spacing factor for test concentrations: approx. 1.1 - Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 62.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: converted to active matter
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 195 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 190 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - Mortality of control: none
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 of the test item was found to be 62.4 mg/L a.i.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 2008-08-21 to 2008-08-25
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- 0, 96h
- Vehicle:
- no
- Details on test solutions:
- direct weighing, limit test at 100 mg/L test item (29.8 mg/L a.i.)
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Hardness:
- Total Hardness 59 mg/L as CaCO3
- Test temperature:
- 22.3 degree C
- pH:
- 7.23-7.62
- Dissolved oxygen:
- Oxygen saturation 95-100%
- Nominal and measured concentrations:
- nominal 100 mg/L test item concentration, 16.6 mg/L DOC of test media
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 29.8 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 29.8 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 29.8 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Executive summary:
In this static limit test according OECD 203 the test item Hostapon SG (a.i content of solution 29.8% ww) did not cause any effects to zebrafish after 96h when tested with a nominal concentration of 100 mg/L (29.8 mg/L a.i.). LC0 and NOEC are 100 mg/L (29.8 mg/L a.i.). LC100 is > 100 mg/L (> 29.8 mg/L a.i.).
Validity criteria on Oxygen saturation (>= 60%) and Mortality in the control (0%) were met.
Referenceopen allclose all
Description of key information
LC50 (96h) = 62.4 mg/L (nominal, based on active matter) for Leuciscus idus (OECD 203, read across)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 62.4 mg/L
Additional information
No study is available on The test item. Two studies from supporting substance (structural analogue or surrogate) are available.
In this static limit test according OECD 203 the test item Sodium-N-cocoyl glycinate (a.i content of solution 29.8% ww) did not cause any effects to zebrafish after 96h when tested with a nominal concentration of 100 mg/L (29.8 mg/L a.i.). LC0 and NOEC are 100 mg/L (29.8 mg/L a.i.). LC100 is > 100 mg/L (> 29.8 mg/L a.i.).
In a static test according OECD 203 the test item Sodium N-octoyl glutamate the LC50 of the test item was found to be 150 mg/L test item or 62.4 mg/L a.i.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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