Registration Dossier

Administrative data

Description of key information

- Acute toxicity:

Oral: LD50: >2000 mg/kg in the rat

Dermal: LD50: > 2000 mg/kg in the rat

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Additional information

Data are available from studies investigating effects following exposure via the oral and dermal routes of administration. No significant toxicities were apparent at limit doses of 2000 mg/kg body weight.

Justification for selection of acute toxicity – oral endpoint

Single study available for evaluation

Justification for selection of acute toxicity – dermal endpoint

Single study available for evaluation

Justification for classification or non-classification

Classification with regard to acute oral and dermal toxicity is not justified based on the observed lack of mortality at a dose level of 2000 mg/kg.