Registration Dossier
Registration Dossier
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EC number: 205-324-8 | CAS number: 138-32-9
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Study period:
- 1996
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Peer reviewed handbook data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Not specified - handbook data
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- Cetrimonium chloride
- EC Number:
- 203-928-6
- EC Name:
- Cetrimonium chloride
- Cas Number:
- 112-02-7
- Molecular formula:
- C19H42N.Cl
- IUPAC Name:
- N,N,N-trimethylhexadecan-1-aminium chloride
- Test material form:
- solid: crystalline
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intravenous
- Vehicle:
- not specified
- Details on exposure:
- Not specified
- Doses:
- Not specified
- No. of animals per sex per dose:
- Not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 325 mg/kg bw
- Mortality:
- Not specified
- Clinical signs:
- Not specified
- Body weight:
- Not specified
- Gross pathology:
- Not specified
- Other findings:
- Not specified
Applicant's summary and conclusion
- Conclusions:
- LD50 Mouse iv 325 mg/kg (Handbook value)
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