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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Justification for type of information:
Calculation of the Partition Coefficient (Pow) based on Water Solubility
and 1-Octanol Solubility of Carbazat (KGD1409)
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
Currenta internal SOP 00187 Version 3, this SOP corresponds to the Council Regulations EC No 440/2008, Guideline Part A – Methods for
the Determination of the physical-chemical properties, A.8, “Partition Coefficient” (adopted, May 2008) and to the OECD guideline for
testing of chemicals No: 107 and No: 117 “Partition Coefficient
(n-octanol/water)“ (adopted 27 July 1995 and 13 April 2004)
GLP compliance:
yes
Other quality assurance:
other:
Type of method:
calculation method (fragments)
Partition coefficient type:
octanol-water
Analytical method:
other: Calculation
Key result
Type:
log Pow
Partition coefficient:
ca. 0
Temp.:
20 °C
pH:
ca. 7

Description of key information

The partition coefficient (Pow) of Carbazat (KGD1409),batch no.: P2D5000133,was calculated, becausethe test item Carbazat (KGD1409) was soluble in demineralized water in each ratio (see study 2014/0074/04) and soluble in 1-octanol in each ratio (see study 2014/0074/12).

 

 

The calculated partition coefficient of the test itemCarbazat (KGD1409)at 20 °C is:

log Pow: 0.0

Key value for chemical safety assessment

Log Kow (Log Pow):
0

Additional information