Registration Dossier

Administrative data

Description of key information

The genotoxicity of the substance has been assessed in vitro for three genotoxicity endpoints: genotoxicity in bacteria, cytogenicity in a chromosomal aberration assay and genemutation test in mammalian cells, resulting in the absence of genotoxicity.

Key value for chemical safety assessment

Mode of Action Analysis / Human Relevance Framework

In view of the absence of in vitro genotoxicity the substance does not have a genotoxic Mode of Action.

Additional information

Justification for classification or non-classification

The genotoxicity of the substance has been assessed in vitro for three genotoxicity endpoints: genotoxicity in bacteria, cytogenicity in a chromosomal aberration assay and genemutation test in mammalian cells, resulting in the absence of genotoxicity. Therefore no genotoxic carcinogenicity is expected, via the oral, inhalation and dermal route. The substance does not need to be classified for genotoxic carcinogenicity via the oral, inhalation and dermal route in accordance with the criteria outlined in the EU CLP (EC no. 1272/2008/EC and its updates).