Registration Dossier

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Recent guideline study not to GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Principles of method if other than guideline:
The solubility of the substance in n-octanol and water was separately determined then the Pow calculated as n-octanol solubility/water solubility.
GLP compliance:
no
Type of method:
other: Ratio of measured solubilities
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Benzenesulfonic acid, 4-C10-13-sec-alkyl derivs., compds. with 2-propanamine
EC Number:
284-664-9
EC Name:
Benzenesulfonic acid, 4-C10-13-sec-alkyl derivs., compds. with 2-propanamine
Cas Number:
84961-74-0
IUPAC Name:
Benzenesulfonic acid, 4-C10-13-sec-alkyl derivs.-, compd. with 2-propanamine (1:1)
Test material form:
not specified

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 0.51
Temp.:
20 °C
Remarks on result:
other: Determined by ratio of solubilities in n-octanol and water
Details on results:
The solubility in n-octanol was determined to be >750 g/L at 20 degC. The water solubility was determined to be >230 g/L. Therefore the Pow is calcuated as >750/230 = > 3.26. Therefore the log Pow is >0.51

Applicant's summary and conclusion

Conclusions:
The substance has a log Pow of >0.51