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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Endpoint:
short-term toxicity to aquatic invertebrates
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
The target substance is hydrolytically unstable with hydrolysis half-life less than 5 minute. The hydrolysis products include 1-propanol and hydrated zirconium dioxide. The ecotoxicity data of the organic parts have been well-investigated and used for read-across.
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
according to
Guideline:
other: DIN 38412 Part 11, Daphnia- Short term test
GLP compliance:
not specified
Analytical monitoring:
no
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 3 644 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Validity criteria fulfilled:
yes
Conclusions:
The 48h CC50, flow though method, tesed on Daphnia magna was 3644 mg/l for 1-propanol

Description of key information

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
3 644 mg/L

Additional information

No studies were conducted on the target substance, Zirconium tetrapropanolate. As the target substance hydrolyses rapidly (half-life < 5 minutes) the intrinsic properties are related to hydrolysis products of the target substance.

On the basis that if entering the environmental, this substance will quickly dissociate to form the inorganic (poorly soluble) zirconium dioxide and well-evaluated organic substances – 1-propanol.

The zirconium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.

EC50 (48h) values tested on Daphnia magna were 3644 mg/l for1-propanol (Kuehn, et al. 1989). This value was used for CSA.