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Ecotoxicological information

Short-term toxicity to fish

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Endpoint:
short-term toxicity to fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
The target substance is hydrolytically unstable with hydrolysis half-life less than 5 minute. The hydrolysis products include 1-propanol and hydrated zirconium dioxide. The ecotoxicity data of the organic parts have been well-investigated and used for read-across.
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified
Analytical monitoring:
yes
Test organisms (species):
Pimephales promelas
Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 4 480 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 4 630 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
yes
Conclusions:
The 96h LC50, flow through method, tested on Pimephales promelas (Fathead minnow) was 4630 to 4480 mg/l. The lower value was chosen for CSA.

Description of key information

Key value for chemical safety assessment

LC50 for freshwater fish:
4 630 mg/L

Additional information

No studies were conducted on the target substance, Zirconium tetrapropanolate. As the target substance hydrolyses rapidly (half-life < 5 minutes) the intrinsic properties are related to hydrolysis products of the target substance.

On the basis that if entering the environmental, this substance will quickly dissociate to form the inorganic (poorly soluble) zirconium dioxide and well-evaluated organic substances – 1-propanol.

The zirconium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.

LC50 (96h) values tested on Pimephales promelas were 4630-4480 mg/l for1-propanol (Geiger, et al. 1984). The lowest value of 4630 mg/l was chosen for CSA.