Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The experimental work associated with this study was carried out between 11 November 2016 and 22 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
GLP compliance:
yes (incl. QA statement)
Type of method:
differential thermal analysis

Test material

Constituent 1
Chemical structure
Reference substance name:
Pidolic acid
EC Number:
202-700-3
EC Name:
Pidolic acid
Cas Number:
98-79-3
Molecular formula:
C5H7NO3
IUPAC Name:
(2S)-5-oxopyrrolidine-2-carboxylic acid
Test material form:
solid: particulate/powder
Details on test material:
white solid crystalline powder
Specific details on test material used for the study:
Test substances: (2S)-5-oxopyrrolidine-2-carboxylic acid Technical Materials
Acid Source: (2S)-5-oxopyrrolidine-2-carboxylic acid (Acid Source)
Salt Source: (2S)-5-oxopyrrolidine-2-carboxylic acid (Potassium Salt)
Received on: 8th November 2016
DNAL Sample Numbers: DNA3730/1-2
Reference Standard: (S)-(-)-2-Pyrrolidinone-5-carboxylic acid reference standard
Received on: 6th January 2017

Results and discussion

Boiling point
Key result
Boiling pt.:
ca. 226.2 °C
Decomposition:
yes
Decomp. temp.:
ca. 226.2 °C

Any other information on results incl. tables

No significant deviation was recorded in this part of the study.

 Analysis/Test  Method  Sample Reference Standard
 Boiling Point  OECD 103

 Ref standard A: the sample started to decompose and boil at the same time at 226.4 deg C

Ref standard B: the sample started to decompose and boil at the same time at 226.0 deg C.

Mean: 226.2 deg C.

Applicant's summary and conclusion

Conclusions:
According to the results obtained in this test, the sample started to decompose and boil at the same time at 226.2 deg C.