Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Toxicology and Applied Pharmacology. Vol. 63, Pg. 150
Year:
1982
Bibliographic source:
Toxicology and Applied Pharmacology. Vol. 63

Materials and methods

Principles of method if other than guideline:
Not available
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
152 mg/kg bw
Clinical signs:
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: ATAXIA
BEHAVIORAL: ANTIPSYCHOTIC

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria