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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From July 2016 to January 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Batch No.of test material: 24/02/2016
- Expiration date of the lot/batch: July 2021
- Purity test date: July 2016

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: In darkness at room temperature
Key result
Melting / freezing pt.:
< -100 °C

For the melting point, seven assays were performed. However, crucible position and software connection problems occured for the assays No. 1 to 5. The assays No. 6 and 7 were taken into account.

In these assay, the cooling phase was from about 25 °C to -100 °C at 10 °C/min. (Isotherm at about -100 °C for 15 min) and the heating phase was from -100 °C to 25 °C at 5 °C/min (Isotherm at 25 °C for 10 min).

In these 2 assays no freezing point of the test item was recorded down to -100 °C.

Conclusions:
The freezing point of the test item is < - 100°C.
Executive summary:

The freezing point of the test item was determined with Differential Scanning Calorimetry (DSC) according to recognized guidelines (OECD Guideline 102 and EU Method A.1) and under GLP compliance. No deviations from the guidelines have been observed during the test.

No endothermic peak was observed during the DSC experiments.

Therefore, the freezing point of the test item is considered to be < - 100°C.

Description of key information

One reliable study (Klimisch 1) is available.

The freezing point of the test item was determined with Differential Scanning Calorimetry (DSC) according to recognized guidelines (OECD Guideline 102 and EU Method A.1).

The study was GLP compliant and no deviation from the guidelines was observed during the test.

No endothermic peak was observed during the DSC experiments.

Therefore, the freezing point of the test item is considered to be < - 100°C.

Key value for chemical safety assessment

Additional information