Registration Dossier
Registration Dossier
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EC number: 247-761-7 | CAS number: 26530-20-1
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Assessment as woodpreservative under Regulation (EU) 528/2012
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-octyl-2H-isothiazol-3-one
- EC Number:
- 247-761-7
- EC Name:
- 2-octyl-2H-isothiazol-3-one
- Cas Number:
- 26530-20-1
- Molecular formula:
- C11H19NOS
- IUPAC Name:
- 2-octyl-2H-isothiazol-3-one
- Reference substance name:
- dihydrogen oxide
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- dihydrogen oxide
- Test material form:
- liquid
Constituent 1
impurity 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- other: no data
- Basis:
- mean
- Score:
- 80
- Max. score:
- 110
- Reversibility:
- not reversible
- Remarks on result:
- positive indication of irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (irreversible effects on the eye) based on GHS criteria
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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