Registration Dossier
Registration Dossier
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EC number: 216-322-1 | CAS number: 1559-34-8
Endpoint summary
Administrative data
Description of key information
Oral LD50 data in rats: 2630 mg/kgbw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 630 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In an old but well reported acute oral toxicity study than followed the key principles of a guideline study, the substance 3,6,9,12-tetraoxahexadecan-1-ol was given to rats in single oral doses up to 6400ul/kg and the rats observed for 7 days. Based on the level of mortality seen, an LD50 of around 2600mg/kg was determined.
Justification for classification or non-classification
The LD50 by the dermal route and the oral route are greater than the cut off dose of 200mg/kg and therefore classification is not required. No adverse effects are seen following inhalation exposure to saturated vapour concentrations and therefore no classification by this route is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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